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The line's engaged tadacip cost Glaxo last year agreed to pay $3 billion and plead guilty tocriminal charges in one of the largest healthcare fraud cases inU.S. history. That case involved marketing of products forunapproved uses, including the antidepressant Paxil to underagepatients. That settlement also involved charges of failing toprovide the U.S. Food and Drug Administration with Avandiasafety data.