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I like watching TV fda black box warning misoprostol It said that people with a high urine output have a lower rate of kidney stone disease, that the flushing action of the water may reduce the risk of a urinary tract infection (especially in women after sex). Perhaps most importantly, they referenced a surprising study which showed that paradoxically an increased intake of water increased the risk of bladder cancer. But only tap water. And there's the clue.